Precision medicine is revolutionizing healthcare by tailoring treatments to individual patients based on their unique genetic and proteomic profiles. Genomics, the exploration of an organism's complete set of DNA, allows us to discover disease-causing mutations and predict an individual's susceptibility to certain conditions. Proteomics, conversely

. Such experiments are referred to as mutation accumulation (MA) experiments (Elena and Lenski 2003; Lind and Andersson 2008; Brockhurst et al. 2010). It is now attainable to comply with up MA experiments with complete-genome sequencing on the ancestor strain and its ensuing progeny, Hence letting to the genome-huge identification with the MA mutat